2JG8

Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine

2JG8 の概要

• エントリーDOI: 10.2210/pdb2jg8/pdb
• 関連するPDBエントリー: 1PK6 2JG9
• 分子名称: Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, ... (7 entities in total)
• 機能のキーワード: polymorphism, glycoprotein, phagocytosis, disease mutation, complement pathway, immune system, cell surface molecule, pyrrolidone carboxylic acid, hydroxylation, innate immunity, immune response, collagen, tolerance, apopotosis, complement
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 90374.15

構造登録者

Paidassi, H.,Tacnet-Delorme, P.,Garlatti, V.,Darnault, C.,Ghebrehiwet, B.,Gaboriaud, C.,Arlaud, G.J.,Frachet, P. (登録日: 2007-02-09, 公開日: 2008-02-19, 最終更新日: 2023-12-13)

• 主引用文献: Paidassi, H.,Tacnet-Delorme, P.,Garlatti, V.,Darnault, C.,Ghebrehiwet, B.,Gaboriaud, C.,Arlaud, G.J.,Frachet, P.; C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition.; J.Immunol., 180:2329-2338, 2008; PubMed: 18250442; DOI: 10.4049/jimmunol.180.4.2329

実験手法

X-RAY DIFFRACTION (2.05 Å)