2JF4

Family 37 trehalase from Escherichia coli in complex with validoxylamine

2JF4 の概要

• エントリーDOI: 10.2210/pdb2jf4/pdb
• 分子名称: PERIPLASMIC TREHALASE, (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL (3 entities in total)
• 機能のキーワード: family 37, hydrolase, inhibitor, trehalase, glycoside hydrolase, periplasmic, glycosidase, validoxylamine
• 由来する生物種: ESCHERICHIA COLI
• 細胞内の位置: Periplasm: P13482
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61518.40

構造登録者

Gibson, R.P.,Gloster, T.M.,Roberts, S.,Warren, R.A.J.,Storch De Gracia, I.,Garcia, A.,Chiara, J.L.,Davies, G.J. (登録日: 2007-01-25, 公開日: 2007-02-13, 最終更新日: 2024-11-13)

• 主引用文献: Gibson, R.P.,Gloster, T.M.,Roberts, S.,Warren, R.A.J.,Storch De Gracia, I.,Garcia, A.,Chiara, J.L.,Davies, G.J.; Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors.; Angew.Chem.Int.Ed.Engl., 46:4115-, 2007; PubMed: 17455176; DOI: 10.1002/ANIE.200604825

実験手法

X-RAY DIFFRACTION (2.2 Å)