2JCQ

The hyaluronan binding domain of murine CD44 in a Type A complex with an HA 8-mer

2JCQ の概要

• エントリーDOI: 10.2210/pdb2jcq/pdb
• 関連するPDBエントリー: 2JCP 2JCR
• 分子名称: CD44 ANTIGEN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: sugar-binding protein, hyauronan, link-domain, proteoglycan, blood group antigen, lectin, antigen, membrane, receptor, sulfation, glycoprotein, c-type lectin, cell adhesion, extracellular matrix, pyrrolidone carboxylic acid, transmembrane, sugar- binding, phosphorylation, sugar binding protein
• 由来する生物種: MUS MUSCULUS (HOUSE MOUSE)
• 細胞内の位置: Cell membrane ; Single-pass type I membrane protein : P15379
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18580.30

構造登録者

Banerji, S.,Wright, A.J.,Noble, M.E.M.,Mahoney, D.J.,Campbell, I.D.,Day, A.J.,Jackson, D.G. (登録日: 2007-01-03, 公開日: 2007-01-30, 最終更新日: 2023-12-13)

• 主引用文献: Banerji, S.,Wright, A.J.,Noble, M.E.M.,Mahoney, D.J.,Campbell, I.D.,Day, A.J.,Jackson, D.G.; Structures of the Cd44-Hyaluronan Complex Provide Insight Into a Fundamental Carbohydrate-Protein Interaction.; Nat.Struct.Mol.Biol., 14:234-, 2008; PubMed: 17293874; DOI: 10.1038/NSMB1201

実験手法

X-RAY DIFFRACTION (1.25 Å)