2JAL

Beta-glucosidase from Thermotoga maritima in complex with cyclophellitol

Summary for 2JAL

Entry DOI	10.2210/pdb2jal/pdb
Related	1OD0 1OIF 1OIM 1OIN 1UZ1 1W3J 2CBU 2CBV 2CES 2CET 2J75 2J77 2J78 2J79 2J7B 2J7C 2J7D 2J7E 2J7F 2J7G 2J7H
Descriptor	BETA-GLUCOSIDASE A, (1R,2S,3S,4S,5R,6R)-6-(HYDROXYMETHYL)CYCLOHEXANE-1,2,3,4,5-PENTOL, ACETATE ION, ... (5 entities in total)
Functional Keywords	polysaccharide degradation, glycosidase, glycoside hydrolase, cellulose degradation, carbohydrate metabolism, family 1, covalent, hydrolase, inhibitor
Biological source	THERMOTOGA MARITIMA
Total number of polymer chains	2
Total formula weight	108427.83
Authors	Gloster, T.M.,Madsen, R.,Davies, G.J. (deposition date: 2006-11-29, release date: 2007-01-03, Last modification date: 2024-11-06)
Primary citation	Gloster, T.M.,Madsen, R.,Davies, G.J. Structural Basis for Cyclophellitol Inhibition of a Beta-Glucosidase. Org.Biomol.Chem., 5:444-, 2007 Cited by PubMed Abstract: The structural basis for beta-glucosidase inhibition by cyclophellitol is demonstrated using X-ray crystallography, enzyme kinetics and mass spectrometry. PubMed: 17252125 DOI: 10.1039/B616590G PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation