2J8Q

Crystal structure of human cleavage and polyadenylation specificity factor 5 (CPSF5) in complex with a sulphate ion.

Summary for 2J8Q

• Entry DOI: 10.2210/pdb2j8q/pdb
• Related: 2CL3
• Descriptor: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5, SULFATE ION (3 entities in total)
• Functional Keywords: nuclear protein, rna-binding, mrna processing, phosphorylation, 3'mrna cleavage and polyadenylation factor
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus: O43809
• Total number of polymer chains: 2
• Total formula weight: 53032.76

Authors

Moche, M.,Stenmark, P.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg, S.L.,Hogbom, M.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Magnusdottir, A.,Nilsson, M.E.,Nilsson-Ehle, P.,Nyman, T.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Upsten, M.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2006-10-27, release date: 2006-11-13, Last modification date: 2023-12-13)

• Primary citation: Tresaugues, L.,Stenmark, P.,Schuler, H.,Flodin, S.,Welin, M.,Nyman, T.,Hammarstrom, M.,Moche, M.,Graslund, S.,Nordlund, P.; The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site.; Proteins, 73:1047-, 2008; PubMed: 18767156; DOI: 10.1002/PROT.22198

Experimental method

X-RAY DIFFRACTION (2.3 Å)