2J7I

ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER

2J7I の概要

• エントリーDOI: 10.2210/pdb2j7i/pdb
• 関連するPDBエントリー: 1CDB 1GYA 1HNF 1L2Z 2BZ8 2J6F 2J6K 2J6O
• 分子名称: CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2 (3 entities in total)
• 機能のキーワード: coiled coil, polymorphism, glycoprotein, cell adhesion, egfr downregulation, immunoglobulin domain, transmembrane, phosphorylation, adaptor protein, cms, cd2ad, membrane, sh3 domain, sh3-binding, sh3 domain recognition, protein binding
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton : Q9Y5K6; Membrane; Single-pass type I membrane protein: P06729
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 17063.33

構造登録者

Moncalian, G.,Cardenes, N.,Deribe, Y.L.,Spinola-Amilibia, M.,Dikic, I.,Bravo, J. (登録日: 2006-10-09, 公開日: 2006-11-06, 最終更新日: 2017-07-05)

• 主引用文献: Moncalian, G.,Cardenes, N.,Deribe, Y.L.,Spinola-Amilibia, M.,Dikic, I.,Bravo, J.; Atypical Polyproline Recognition by the Cms N-Terminal Src Homology 3 Domain.; J.Biol.Chem., 281:38845-, 2006; PubMed: 17020880; DOI: 10.1074/JBC.M606411200

実験手法

X-RAY DIFFRACTION (2.9 Å)