2J0X

CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)

Summary for 2J0X

Entry DOI	10.2210/pdb2j0x/pdb
Related	1OHI 2J0W
Descriptor	LYSINE-SENSITIVE ASPARTOKINASE 3, ASPARTIC ACID, LYSINE, ... (5 entities in total)
Functional Keywords	feedback inhibition, allosteric regulation, aspartokinase, aspartate pathway, lysine biosynthesis, lysine, kinase, act domain, transferase, amino acid biosynthesis, amino-acid biosynthesis
Biological source	ESCHERICHIA COLI
Total number of polymer chains	2
Total formula weight	97681.40
Authors	Kotaka, M.,Ren, J.,Lockyer, M.,Hawkins, A.R.,Stammers, D.K. (deposition date: 2006-08-07, release date: 2006-08-10, Last modification date: 2024-05-01)
Primary citation	Kotaka, M.,Ren, J.,Lockyer, M.,Hawkins, A.R.,Stammers, D.K. Structures of R- and T-State Escherichia Coli Aspartokinase III: Mechanisms of the Allosteric Transition and Inhibition by Lysine. J.Biol.Chem., 281:31544-, 2006 Cited by PubMed: 16905770 DOI: 10.1074/JBC.M605886200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation