Crystal structure of human cyclin T2 at 1.8 A resolution

Summary for 2IVX

DescriptorCYCLIN-T2, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywordstranscription regulation, cell division, phosphorylation, nuclear protein, cyclin, cell cycle, transcription
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight60019.24
Primary citation
Baumli, S.,Lolli, G.,Lowe, E.D.,Troiani, S.,Rusconi, L.,Bullock, A.N.,Debreczeni, J.E.,Knapp, S.,Johnson, L.N.
The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
EMBO J., 27:1907-1918, 2008
PubMed: 18566585 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2008.121
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22430 0.9% 3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution