2IVX

Crystal structure of human cyclin T2 at 1.8 A resolution

2IVX の概要

• エントリーDOI: 10.2210/pdb2ivx/pdb
• 分子名称: CYCLIN-T2, 1,2-ETHANEDIOL (3 entities in total)
• 機能のキーワード: transcription regulation, cell division, phosphorylation, nuclear protein, cyclin, cell cycle, transcription
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60019.24

構造登録者

Debreczeni, J.E.,Bullock, A.N.,Fedorov, O.,Savitsky, P.,Berridge, G.,Das, S.,Pike, A.C.W.,Turnbull, A.,Ugochukwu, E.,Papagrigoriou, E.,Gorrec, F.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,Weigelt, J.,von Delft, F.,Knapp, S. (登録日: 2006-06-21, 公開日: 2006-07-19, 最終更新日: 2024-05-08)

• 主引用文献: Baumli, S.,Lolli, G.,Lowe, E.D.,Troiani, S.,Rusconi, L.,Bullock, A.N.,Debreczeni, J.E.,Knapp, S.,Johnson, L.N.; The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.; EMBO J., 27:1907-1918, 2008; PubMed: 18566585; DOI: 10.1038/emboj.2008.121

実験手法

X-RAY DIFFRACTION (1.8 Å)