2ITG

CATALYTIC DOMAIN OF HIV-1 INTEGRASE: ORDERED ACTIVE SITE IN THE F185H CONSTRUCT

2ITG の概要

• エントリーDOI: 10.2210/pdb2itg/pdb
• 分子名称: HUMAN IMMUNODEFICIENCY VIRUS-1 INTEGRASE (2 entities in total)
• 機能のキーワード: dna integration, aids, polyprotein, hydrolase, endonuclease, polynucleotidyl transferase, dna binding (viral)
• 由来する生物種: Human immunodeficiency virus 1
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17921.45

構造登録者

Bujacz, G.,Alexandratos, J.,Wlodawer, A.,Zhou-Liu, Q.,Clement-Mella, C. (登録日: 1996-09-13, 公開日: 1997-03-12, 最終更新日: 2024-05-29)

• 主引用文献: Bujacz, G.,Alexandratos, J.,Qing, Z.L.,Clement-Mella, C.,Wlodawer, A.; The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant.; FEBS Lett., 398:175-178, 1996; PubMed: 8977101; DOI: 10.1016/S0014-5793(96)01236-7

実験手法

X-RAY DIFFRACTION (2.6 Å)