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2IT8

Solution structure of a linear analog of the cyclic squash trypsin inhibitor MCoTI-II

Summary for 2IT8
Entry DOI10.2210/pdb2it8/pdb
Related1HA9 1IB9 2C4B 2IT7
NMR InformationBMRB: 7361
DescriptorTrypsin inhibitor 2 (1 entity in total)
Functional Keywordsplant protein analog, knottin, cystine-knot, 3-10 helix, triple-stranded anti-parallel beta-sheet, plant protein
Biological sourceMomordica cochinchinensis (Spiny bitter cucumber)
Cellular locationSecreted: P82409
Total number of polymer chains1
Total formula weight3077.70
Authors
Avrutina, O.,Chiche, L.,Diederichsen, U.,Heitz, A.,Kolmar, H. (deposition date: 2006-10-19, release date: 2007-10-02, Last modification date: 2024-11-20)
Primary citationHeitz, A.,Avrutina, O.,Le-Nguyen, D.,Diederichsen, U.,Hernandez, J.F.,Gracy, J.,Kolmar, H.,Chiche, L.
Knottin cyclization: Structure and stability of cyclic and linear squash inhibitors do not differ significantly
To be Published,
Experimental method
SOLUTION NMR
Structure validation

227561

數據於2024-11-20公開中

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