2ILP

Clostridium botulinum Serotype A Light Chain inhibited by 4-chlorocinnamic hydroxamate

2ILP の概要

• エントリーDOI: 10.2210/pdb2ilp/pdb
• 分子名称: Botulinum neurotoxin A light-chain, ZINC ION, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: clostridium botulinum neurotoxin, type a, substrate specificity, substrate switching, protease inhibitors, hydrolase
• 由来する生物種: Clostridium botulinum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102255.57

構造登録者

Silvaggi, N.R.,Allen, K.N. (登録日: 2006-10-03, 公開日: 2007-06-05, 最終更新日: 2024-02-21)

• 主引用文献: Silvaggi, N.R.,Boldt, G.E.,Hixon, M.S.,Kennedy, J.P.,Tzipori, S.,Janda, K.D.,Allen, K.N.; Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility.; Chem.Biol., 14:533-542, 2007; PubMed: 17524984; DOI: 10.1016/j.chembiol.2007.03.014

実験手法

X-RAY DIFFRACTION (1.9 Å)