2I83

hyaluronan-binding domain of CD44 in its ligand-bound form

Summary for 2I83

DescriptorCD44 antigen (1 entity in total)
Functional Keywordslink module, cell adhesion
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P16070
Total number of polymer chains1
Total molecular weight17732.69
Authors
Takeda, M.,Ogino, S.,Umemoto, R.,Sakakura, M.,Kajiwara, M.,Sugahara, K.N.,Hayasaka, H.,Miyasaka, M.,Terasawa, H.,Shimada, I. (deposition date: 2006-09-01, release date: 2006-11-21, Last modification date: 2011-07-13)
Primary citation
Takeda, M.,Ogino, S.,Umemoto, R.,Sakakura, M.,Kajiwara, M.,Sugahara, K.N.,Hayasaka, H.,Miyasaka, M.,Terasawa, H.,Shimada, I.
Ligand-induced Structural Changes of the CD44 Hyaluronan-binding Domain Revealed by NMR
J.Biol.Chem., 281:40089-40095, 2006
PubMed: 17085435 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M608425200
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers91.9%10.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures