2I3C
Crystal Structure of an Aspartoacylase from Homo Sapiens
Summary for 2I3C
Entry DOI | 10.2210/pdb2i3c/pdb |
Related | 2gu2 |
Descriptor | Aspartoacylase, ZINC ION, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | canavan disease, n-acetyl-l-aspartate, zinc-dependent hydrolase, aspartoacylase family, aminoacylase-2, acy2, aspa, protein structure initiative, psi, center for eukaryotic structural genomics, cesg, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P45381 |
Total number of polymer chains | 2 |
Total formula weight | 73269.72 |
Authors | Bitto, E.,Wesenberg, G.E.,Phillips Jr., G.N.,Mccoy, J.G.,Bingman, C.A.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2006-08-17, release date: 2006-08-29, Last modification date: 2023-11-15) |
Primary citation | Bitto, E.,Bingman, C.A.,Wesenberg, G.E.,McCoy, J.G.,Phillips, G.N. Structure of aspartoacylase, the brain enzyme impaired in Canavan disease. Proc.Natl.Acad.Sci.Usa, 104:456-461, 2007 Cited by PubMed: 17194761DOI: 10.1073/pnas.0607817104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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