Summary for 2HX3
| Related | 1P6I 2HX2 2HX4 |
|---|---|
| Descriptor | Nitric-oxide synthase, ACETATE ION, ZINC ION, ... (7 entities in total) |
| Functional Keywords | nitric oxide synthase, heme enzyme, inhibitor, oxidoreductase |
| Biological source | Rattus norvegicus (Norway rat) |
| Cellular location | Cell membrane, sarcolemma; Peripheral membrane protein (By similarity) P29476 |
| Total number of polymer chains | 2 |
| Total molecular weight | 100050.61 |
| Authors | Igarashi, J.,Li, H.,Poulos, T.L. (deposition date: 2006-08-02, release date: 2007-04-24, Last modification date: 2011-07-13) |
| Primary citation | Seo, J.,Igarashi, J.,Li, H.,Martasek, P.,Roman, L.J.,Poulos, T.L.,Silverman, R.B. Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water. J.Med.Chem., 50:2089-2099, 2007 PubMed: 17425297 (PDB entries with the same primary citation) DOI: 10.1021/jm061305c  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
