2HWZ
Fab fragment of Humanized anti-viral antibody MEDI-493 (Synagis TM)
Summary for 2HWZ
Entry DOI | 10.2210/pdb2hwz/pdb |
Descriptor | Immunoglobulin Fab light chain, Immunoglobulin Fab heavy chain (3 entities in total) |
Functional Keywords | immunoglobulin, fab fragment, immune system |
Biological source | Homo sapiens, Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 47424.24 |
Authors | Braden, B. (deposition date: 2006-08-02, release date: 2007-08-14, Last modification date: 2021-02-03) |
Primary citation | Wei, Z.,Feng, J.,Lin, H.-Y.,Mullapudi, S.,Bishop, E.,Tous, G.,Casas-Finet, J.,Hakki, F.,Strouse, R.,Schenerman, M. Identification of a single tryptophan residue as critical for binding activity in a humanized monoclonal antibody against respiratory syncytial virus To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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