2HWZ

Fab fragment of Humanized anti-viral antibody MEDI-493 (Synagis TM)

Summary for 2HWZ

• Entry DOI: 10.2210/pdb2hwz/pdb
• Descriptor: Immunoglobulin Fab light chain, Immunoglobulin Fab heavy chain (3 entities in total)
• Functional Keywords: immunoglobulin, fab fragment, immune system
• Biological source: Homo sapiens, Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 47424.24

Authors

Braden, B. (deposition date: 2006-08-02, release date: 2007-08-14, Last modification date: 2021-02-03)

• Primary citation: Wei, Z.,Feng, J.,Lin, H.-Y.,Mullapudi, S.,Bishop, E.,Tous, G.,Casas-Finet, J.,Hakki, F.,Strouse, R.,Schenerman, M.; Identification of a single tryptophan residue as critical for binding activity in a humanized monoclonal antibody against respiratory syncytial virus; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)