2HSX
NMR Structure of the nonstructural protein 1 (nsp1) from the SARS coronavirus
Summary for 2HSX
Entry DOI | 10.2210/pdb2hsx/pdb |
Related | 2gdt |
Descriptor | Leader protein; p65 homolog; NSP1 (EC 3.4.22.-) (1 entity in total) |
Functional Keywords | leader protein, beta-barrel, alpha-beta, virus, replicase, structural genomics, psi-2, protein structure initiative, joint center for structural genomics, jcsg, viral protein, hydrolase |
Biological source | SARS coronavirus |
Cellular location | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 |
Total number of polymer chains | 1 |
Total formula weight | 12680.53 |
Authors | Almeida, M.S.,Herrmann, T.,Geralt, M.,Johnson, M.A.,Saikatendu, K.,Joseph, J.,Subramanian, R.C.,Neuman, B.W.,Buchmeier, M.J.,Stevens, R.C.,Kuhn, P.,Wilson, I.A.,Wuthrich, K.,Joint Center for Structural Genomics (JCSG) (deposition date: 2006-07-24, release date: 2007-02-06, Last modification date: 2021-10-20) |
Primary citation | Almeida, M.S.,Johnson, M.A.,Herrmann, T.,Geralt, M.,Wuthrich, K. Novel beta-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus. J.Virol., 81:3151-3161, 2007 Cited by PubMed: 17202208DOI: 10.1128/JVI.01939-06 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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