2HSK

NMR Structure of 13mer Duplex DNA containing an abasic site (Y) in 5'-CCAAAGYACCGGG-3' (10 structures, alpha anomer)

Summary for 2HSK

• Entry DOI: 10.2210/pdb2hsk/pdb
• Related: 2HOU 2HPX 2HSL 2HSR 2HSS
• Descriptor: 5'-D(*CP*CP*AP*AP*AP*GP*(D1P)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3' (2 entities in total)
• Functional Keywords: abasic site, dna lesion, base excision repair, ape1, dna
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 7836.09

Authors

Chen, J.,Dupradeau, F.Y.,Case, D.A.,Turner, C.J.,Stubbe, J. (deposition date: 2006-07-21, release date: 2007-05-29, Last modification date: 2018-08-08)

• Primary citation: Chen, J.,Dupradeau, F.Y.,Case, D.A.,Turner, C.J.,Stubbe, J.; Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.; Biochemistry, 46:3096-3107, 2007; PubMed: 17323932; DOI: 10.1021/bi6024269

Experimental method

SOLUTION NMR