2HRR
Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Tabun (GA)
Summary for 2HRR
| Entry DOI | 10.2210/pdb2hrr/pdb |
| Related PRD ID | PRD_900003 |
| Descriptor | Liver carboxylesterase 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, R-ETHYL N,N-DIMETHYLPHOSPHONAMIDATE, ... (7 entities in total) |
| Functional Keywords | hydrolase, carboxylesterase, tabun |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 3 |
| Total formula weight | 179526.67 |
| Authors | Fleming, C.D.,Redinbo, M.R. (deposition date: 2006-07-20, release date: 2007-05-01, Last modification date: 2023-08-30) |
| Primary citation | Fleming, C.D.,Edwards, C.C.,Kirby, S.D.,Maxwell, D.M.,Potter, P.M.,Cerasoli, D.M.,Redinbo, M.R. Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun. Biochemistry, 46:5063-5071, 2007 Cited by PubMed: 17407327DOI: 10.1021/bi700246n PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report
