2HRR

Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Tabun (GA)

2HRR の概要

• エントリーDOI: 10.2210/pdb2hrr/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900003
• 分子名称: Liver carboxylesterase 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, R-ETHYL N,N-DIMETHYLPHOSPHONAMIDATE, ... (7 entities in total)
• 機能のキーワード: hydrolase, carboxylesterase, tabun
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 179526.67

構造登録者

Fleming, C.D.,Redinbo, M.R. (登録日: 2006-07-20, 公開日: 2007-05-01, 最終更新日: 2023-08-30)

• 主引用文献: Fleming, C.D.,Edwards, C.C.,Kirby, S.D.,Maxwell, D.M.,Potter, P.M.,Cerasoli, D.M.,Redinbo, M.R.; Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun.; Biochemistry, 46:5063-5071, 2007; PubMed: 17407327; DOI: 10.1021/bi700246n

実験手法

X-RAY DIFFRACTION (2.7 Å)