2HPO

Structure of Aminopeptidase N from E. coli Suggests a Compartmentalized, Gated Active Site

Summary for 2HPO

DescriptorAminopeptidase N, ZINC ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsmultidomain, closed, compartmentalized active site, hydrolase
Biological sourceEscherichia coli K12
Cellular locationCell inner membrane; Peripheral membrane protein; Cytoplasmic side P04825
Total number of polymer chains1
Total molecular weight101690.79
Authors
Addlagatta, A.,Matthews, B.W.,Gay, L. (deposition date: 2006-07-17, release date: 2006-08-15, Last modification date: 2011-07-13)
Primary citation
Addlagatta, A.,Gay, L.,Matthews, B.W.
Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site.
Proc.Natl.Acad.Sci.Usa, 103:13339-13344, 2006
PubMed: 16938892 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0606167103
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.65 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.180401.3%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report