2HLI
Solution structure of Crotonaldehyde-Derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA Adduct in the 5'-CpG-3' Sequence
Summary for 2HLI
| Entry DOI | 10.2210/pdb2hli/pdb |
| Descriptor | DNA dodecamer with S-crotonaldehyde adduct, DNA dodecamer (2 entities in total) |
| Functional Keywords | interstrand dna cross-link; s-crotonaldehyde-dg adduct; 5'-cpg-3' sequence, dna |
| Total number of polymer chains | 2 |
| Total formula weight | 7396.87 |
| Authors | Cho, Y.-J.,Wang, H.,Kozekov, I.D.,Kurtz, A.J.,Jacob, J.,Voehler, M.,Smith, J.,Harris, T.M.,Rizzo, C.J.,Stone, M.P. (deposition date: 2006-07-07, release date: 2006-09-19, Last modification date: 2024-05-01) |
| Primary citation | Cho, Y.-J.,Wang, H.,Kozekov, I.D.,Kozekova, A.,Kurtz, A.J.,Jacob, J.,Voehler, M.,Smith, J.,Harris, T.M.,Rizzo, C.J.,Lloyd, R.S.,Stone, M.P. Orientation of the Crotonaldehyde-Derived N(2)-[3-Oxo-1(S)-methyl-propyl]-dG DNA Adduct Hinders Interstrand Cross-Link Formation in the 5'-CpG-3' Sequence Chem.Res.Toxicol., 19:1019-1029, 2006 Cited by PubMed: 16918240DOI: 10.1021/tx0600604 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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