2HKC

NMR Structure of the IQ-modified Dodecamer CTCGGC[IQ]GCCATC

Summary for 2HKC

• Entry DOI: 10.2210/pdb2hkc/pdb
• Related: 2HKB
• Descriptor: 5'-D(*CP*TP*CP*GP*GP*CP*GP*CP*CP*AP*TP*C)-3', 5'-D(*GP*AP*TP*GP*GP*CP*GP*CP*CP*GP*AP*G)-3', 3-METHYL-3H-IMIDAZO[4,5-F]QUINOLIN-2-AMINE (3 entities in total)
• Functional Keywords: nar1iq3, rmd calculations, anneal, noesy, cosy, refinement, iq, adduct, hca, dna
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 7526.00

Authors

Wang, F.,DeMuro, N.E.,Elmquist, C.E.,Stover, J.S.,Rizzo, C.J.,Stone, M.P. (deposition date: 2006-07-03, release date: 2006-10-03, Last modification date: 2021-11-03)

• Primary citation: Wang, F.,DeMuro, N.E.,Elmquist, C.E.,Stover, J.S.,Rizzo, C.J.,Stone, M.P.; Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.; J.Am.Chem.Soc., 128:10085-10095, 2006; PubMed: 16881637; DOI: 10.1021/ja062004v

Experimental method

SOLUTION NMR