2HJF
Potassium channel kcsa-fab complex with tetrabutylammonium (TBA)
Summary for 2HJF
Entry DOI | 10.2210/pdb2hjf/pdb |
Descriptor | Antibody fragment Heavy chain, Antibody fragment Light chain, Voltage-gated potassium channel, ... (6 entities in total) |
Functional Keywords | potassium channel, ion transport, metal transport |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P0A334 |
Total number of polymer chains | 3 |
Total formula weight | 58224.57 |
Authors | Faraldo-Gomez, J.D.,Kutluay, E.,Jogini, V.,Zhao, Y.,Heginbotham, L.,Roux, B. (deposition date: 2006-06-30, release date: 2006-12-05, Last modification date: 2023-08-30) |
Primary citation | Faraldo-Gomez, J.D.,Kutluay, E.,Jogini, V.,Zhao, Y.,Heginbotham, L.,Roux, B. Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations. J.Mol.Biol., 365:649-662, 2007 Cited by PubMed: 17070844DOI: 10.1016/j.jmb.2006.09.069 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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