2HJF

Potassium channel kcsa-fab complex with tetrabutylammonium (TBA)

2HJF の概要

• エントリーDOI: 10.2210/pdb2hjf/pdb
• 分子名称: Antibody fragment Heavy chain, Antibody fragment Light chain, Voltage-gated potassium channel, ... (6 entities in total)
• 機能のキーワード: potassium channel, ion transport, metal transport
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P0A334
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 58224.57

構造登録者

Faraldo-Gomez, J.D.,Kutluay, E.,Jogini, V.,Zhao, Y.,Heginbotham, L.,Roux, B. (登録日: 2006-06-30, 公開日: 2006-12-05, 最終更新日: 2023-08-30)

• 主引用文献: Faraldo-Gomez, J.D.,Kutluay, E.,Jogini, V.,Zhao, Y.,Heginbotham, L.,Roux, B.; Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations.; J.Mol.Biol., 365:649-662, 2007; PubMed: 17070844; DOI: 10.1016/j.jmb.2006.09.069

実験手法

X-RAY DIFFRACTION (2.9 Å)