2H8I

Crystal Structure of the Bothropstoxin-I complexed with polyethylene glycol

Summary for 2H8I

Entry DOI	10.2210/pdb2h8i/pdb
Descriptor	Phospholipase A2 homolog 1, DI(HYDROXYETHYL)ETHER (3 entities in total)
Functional Keywords	lys49-pla2s, myotoxicity, toxin
Biological source	Bothrops jararacussu (jararacussu)
Cellular location	Secreted: Q90249
Total number of polymer chains	2
Total formula weight	27716.54
Authors	Murakami, M.T.,Arni, R.K. (deposition date: 2006-06-07, release date: 2007-06-19, Last modification date: 2022-12-21)
Primary citation	Murakami, M.T.,Vicotia, M.M.,Abrego, J.R.B.,Lourenzoni, M.R.,Cintra, A.C.O.,Arruda, E.Z.,Tomaz, M.A.,Melo, P.A.,Arni, R.K. Interfacial surface charge and free accessibility to the PLA2-active site-like region are essential requirements for the activity of Lys49 PLA2 homologues Toxicon, 49:378-387, 2007 Cited by PubMed: 17157889 DOI: 10.1016/j.toxicon.2006.10.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation