The cystal structure of the PDZ domain of human PICK1

Summary for 2GZV

DescriptorPRKCA-binding protein (2 entities in total)
Functional Keywordsprotein kinase c, pdz domain, structural genomics, structural genomics consortium, sgc, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, perinuclear region Q9NRD5
Total number of polymer chains1
Total molecular weight12427.16
Primary citation
Elkins, J.M.,Papagrigoriou, E.,Berridge, G.,Yang, X.,Phillips, C.,Gileadi, C.,Savitsky, P.,Doyle, D.A.
Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16:683-694, 2007
PubMed: 17384233 (PDB entries with the same primary citation)
DOI: 10.1110/ps.062657507
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1697006.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution