2GZQ
Phosphatidylethanolamine-binding protein from Plasmodium vivax
Summary for 2GZQ
| Entry DOI | 10.2210/pdb2gzq/pdb |
| Descriptor | Phosphatidylethanolamine-binding protein (2 entities in total) |
| Functional Keywords | structural genomics, psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, lipid binding protein |
| Biological source | Plasmodium vivax (malaria parasite P. vivax) |
| Total number of polymer chains | 1 |
| Total formula weight | 23298.71 |
| Authors | Arakaki, T.L.,Merritt, E.A.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (deposition date: 2006-05-11, release date: 2006-05-23, Last modification date: 2024-11-20) |
| Primary citation | Arakaki, T.,Neely, H.,Boni, E.,Mueller, N.,Buckner, F.S.,Van Voorhis, W.C.,Lauricella, A.,DeTitta, G.,Luft, J.,Hol, W.G.,Merritt, E.A. The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix Acta Crystallogr.,Sect.F, 63:178-182, 2007 Cited by PubMed Abstract: The structure of a putative Raf kinase inhibitor protein (RKIP) homolog from the eukaryotic parasite Plasmodium vivax has been studied to a resolution of 1.3 A using multiple-wavelength anomalous diffraction at the Se K edge. This protozoan protein is topologically similar to previously studied members of the phosphatidylethanolamine-binding protein (PEBP) sequence family, but exhibits a distinctive left-handed alpha-helical region at one side of the canonical phospholipid-binding site. Re-examination of previously determined PEBP structures suggests that the P. vivax protein and yeast carboxypeptidase Y inhibitor may represent a structurally distinct subfamily of the diverse PEBP-sequence family. PubMed: 17329808DOI: 10.1107/S1744309107007580 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
Download full validation report
