2GST

STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE

2GST の概要

• エントリーDOI: 10.2210/pdb2gst/pdb
• 分子名称: GLUTATHIONE S-TRANSFERASE, SULFATE ION, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, ... (4 entities in total)
• 機能のキーワード: glutathione transferase
• 由来する生物種: Rattus rattus (black rat)
• 細胞内の位置: Cytoplasm: P04905
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52832.81

構造登録者

Ji, X.,Armstrong, R.N.,Gilliland, G.L. (登録日: 1993-06-07, 公開日: 1993-10-31, 最終更新日: 2023-08-30)

• 主引用文献: Ji, X.,Johnson, W.W.,Sesay, M.A.,Dickert, L.,Prasad, S.M.,Ammon, H.L.,Armstrong, R.N.,Gilliland, G.L.; Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.; Biochemistry, 33:1043-1052, 1994; PubMed: 8110735; DOI: 10.1021/bi00171a002

実験手法

X-RAY DIFFRACTION (1.8 Å)