Summary for 2GQ2
| Related | 2AF6 |
|---|---|
| Descriptor | Thymidylate synthase thyX, IODIDE ION, POTASSIUM ION, ... (7 entities in total) |
| Functional Keywords | m.tuberculosis, thyx, fdts, tscp, flavin dependent thymidylate synthase, inhibitor design, bivalent drugs, transferase |
| Biological source | Mycobacterium tuberculosis H37Rv |
| Total number of polymer chains | 4 |
| Total molecular weight | 121708.31 |
| Authors | Sampathkumar, P.,Turley, S.,Sibley, C.H.,Hol, W.G. (deposition date: 2006-04-19, release date: 2006-06-27, Last modification date: 2011-07-13) |
| Primary citation | Sampathkumar, P.,Turley, S.,Sibley, C.H.,Hol, W.G. NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. J.Mol.Biol., 360:1-6, 2006 PubMed: 16730023 (PDB entries with the same primary citation) DOI: 10.1016/j.jmb.2006.04.061  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
