2GNC

Crystal structure of srGAP1 SH3 domain in the slit-robo signaling pathway

Summary for 2GNC

• Entry DOI: 10.2210/pdb2gnc/pdb
• Descriptor: SLIT-ROBO Rho GTPase-activating protein 1 (2 entities in total)
• Functional Keywords: beta barrel, signaling protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 2
• Total formula weight: 13505.22

Authors

Li, X.,Liu, Y.,Gao, F.,Bartlam, M.,Wu, J.Y.,Rao, Z. (deposition date: 2006-04-10, release date: 2006-07-18, Last modification date: 2023-10-25)

• Primary citation: Li, X.,Chen, Y.,Liu, Y.,Gao, J.,Gao, F.,Bartlam, M.,Wu, J.Y.,Rao, Z.; Structural Basis of Robo Proline-rich Motif Recognition by the srGAP1 Src Homology 3 Domain in the Slit-Robo Signaling Pathway; J.Biol.Chem., 281:28430-28437, 2006; PubMed: 16857672; DOI: 10.1074/jbc.M604135200

Experimental method

X-RAY DIFFRACTION (1.8 Å)