2GET

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-I (LT)

2GET の概要

• エントリーDOI: 10.2210/pdb2get/pdb
• 関連するPDBエントリー: 2ges 2geu 2gev
• 分子名称: Pantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: homodimer, coa biosynthesis, nucleotide binding, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36808.81

構造登録者

Das, S.,Kumar, P.,Bhor, V.,Surolia, A.,Vijayan, M. (登録日: 2006-03-20, 公開日: 2006-06-06, 最終更新日: 2023-10-25)

• 主引用文献: Das, S.,Kumar, P.,Bhor, V.,Surolia, A.,Vijayan, M.; Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.; Acta Crystallogr.,Sect.D, 62:628-638, 2006; PubMed: 16699190; DOI: 10.1107/S0907444906012728

実験手法

X-RAY DIFFRACTION (2.35 Å)