2G57

Structure of the Phosphorylation Motif of the oncogenic Protein beta-Catenin Recognized By a Selective Monoclonal Antibody

2G57 の概要

• エントリーDOI: 10.2210/pdb2g57/pdb
• NMR情報: BMRB: 7001
• 分子名称: Beta-catenin (1 entity in total)
• 機能のキーワード: beta-catenin oncogenic protein, p-beta-catenin phosphorylated peptide, epitope mapping, antibody, p-beta-catenin-antibody complex, std-nmr, trnoesy, restrained molecular dynamics, bound structure, binding fragment, oncoprotein
• 細胞内の位置: Cytoplasm: P35222
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2928.95

構造登録者

Megy, S.,Bertho, G.,Gharbi-Benarous, J.,Baleux, F.,Benarous, R.,Girault, J.P. (登録日: 2006-02-22, 公開日: 2006-03-28, 最終更新日: 2022-03-09)

• 主引用文献: Megy, S.,Bertho, G.,Gharbi-Benarous, J.,Baleux, F.,Benarous, R.,Girault, J.P.; STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein beta-catenin recognized by a selective monoclonal antibody; Febs Lett., 580:5411-5422, 2006; PubMed: 16996060; DOI: 10.1016/j.febslet.2006.08.084

実験手法

SOLUTION NMR