2G4B

Structure of U2AF65 variant with polyuridine tract

Summary for 2G4B

• Entry DOI: 10.2210/pdb2g4b/pdb
• Related: 2FZR
• Descriptor: 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', Splicing factor U2AF 65 kDa subunit, 1,4-DIETHYLENE DIOXIDE, ... (4 entities in total)
• Functional Keywords: protein-rna complex, rna splicing factor, rna recognition motif, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P26368
• Total number of polymer chains: 2
• Total formula weight: 21107.89

Authors

Sickmier, E.A.,Kielkopf, C.L. (deposition date: 2006-02-21, release date: 2006-07-25, Last modification date: 2023-08-30)

• Primary citation: Sickmier, E.A.,Frato, K.E.,Paranawithana, S.,Shen, H.,Green, M.R.,Kielkopf, C.L.; Structural basis of polypyrimidine tract recognition by the essential splicing factor U2AF65.; Mol.Cell, 23:49-59, 2006; PubMed: 16818232; DOI: 10.1016/j.molcel.2006.05.025

Experimental method

X-RAY DIFFRACTION (2.5 Å)