2G08

X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, product-transition complex analog with Aluminum fluoride

Summary for 2G08

Entry DOI	10.2210/pdb2g08/pdb
Related	2BDU 2G06 2G07 2G09 2G0A
Descriptor	Cytosolic 5'-nucleotidase III, MAGNESIUM ION, ALUMINUM FLUORIDE, ... (4 entities in total)
Functional Keywords	uniprot q9d020, umph-1, cytosolic 5'-nucleotidase iii, pyrimidine 5'-nucleotidase 1, p5n-1, nt5c3 protein, aah38029, bc038029, mm.158936, lead poisoning, structural genomics functional follow-up study, protein structure initiative, psi, center for eukaryotic structural genomics, cesg, hydrolase
Biological source	Mus musculus (house mouse)
Cellular location	Cytoplasm (Potential): Q9D020
Total number of polymer chains	2
Total formula weight	68544.42
Authors	Bitto, E.,Bingman, C.A.,Wesenberg, G.E.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2006-02-11, release date: 2006-04-04, Last modification date: 2023-11-15)
Primary citation	Bitto, E.,Bingman, C.A.,Wesenberg, G.E.,McCoy, J.G.,Phillips, G.N. Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281:20521-20529, 2006 Cited by PubMed: 16672222 DOI: 10.1074/jbc.M602000200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation