2FYL

Haddock model of the complex between double module of LRP, CR56, and first domain of receptor associated protein, RAP-d1.

2FYL の概要

• エントリーDOI: 10.2210/pdb2fyl/pdb
• 関連するPDBエントリー: 1LRE 2FYJ
• NMR情報: BMRB: 5961
• 分子名称: Alpha-2-macroglobulin receptor-associated protein, Low-density lipoprotein receptor-related protein 1, CALCIUM ION (3 entities in total)
• 機能のキーワード: complex, shift-mapping, haddock, interface, surface active protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Endoplasmic reticulum: P30533; Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; Extracellular side. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm: Q07954
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18560.78

構造登録者

Jensen, G.A.,Andersen, O.M.,Bonvin, A.M.,Bjerrum-Bohr, I.,Etzerodt, M.,O'shea, C.,Poulsen, F.M.,Kragelund, B.B. (登録日: 2006-02-08, 公開日: 2006-10-10, 最終更新日: 2022-03-09)

• 主引用文献: Jensen, G.A.,Andersen, O.M.,Bonvin, A.M.,Bjerrum-Bohr, I.,Etzerodt, M.,O'shea, C.,Poulsen, F.M.,Kragelund, B.B.; Binding Site Structure of One LRP-RAP Complex:Implications for a Common Ligand-Receptor Binding Motif.; J.Mol.Biol., 362:700-716, 2006; PubMed: 16938309; DOI: 10.1016/j.jmb.2006.07.013

実験手法

SOLUTION NMR