2FYB

Crystal structure of the catalytic domain of the human beta1,4-galactosyltransferase mutant M339H in complex with Mn and UDP-galactose in open conformation

Summary for 2FYB

Entry DOI	10.2210/pdb2fyb/pdb
Related	2FY7 2FYA 2FYC 2FYD
Descriptor	Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	m339h mutant, complex with udp-galactose and mn, open conformation, transferase
Biological source	Homo sapiens (human)
Cellular location	Isoform Long: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted: P15291
Total number of polymer chains	1
Total formula weight	33232.33
Authors	Ramakrishnan, B.,Ramasamy, V.,Qasba, P.K. (deposition date: 2006-02-07, release date: 2006-03-14, Last modification date: 2023-08-30)
Primary citation	Ramakrishnan, B.,Ramasamy, V.,Qasba, P.K. Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol., 357:1619-1633, 2006 Cited by PubMed: 16497331 DOI: 10.1016/j.jmb.2006.01.088 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation