2FWP

Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H59N from the acidophilic bacterium Acetobacter aceti, bound to isocair

Summary for 2FWP

• Entry DOI: 10.2210/pdb2fwp/pdb
• Related: 1U11
• Descriptor: N5-carboxyaminoimidazole ribonucleotide mutase, (4R)-5-IMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-4,5-DIHYDRO-1H-IMIDAZOLE-4-CARBOXYLIC ACID, CITRIC ACID, ... (4 entities in total)
• Functional Keywords: acidophile, pure, purine biosynthesis, isocair, lyase
• Biological source: Acetobacter aceti
• Total number of polymer chains: 2
• Total formula weight: 38248.65

Authors

Starks, C.M.,Kappock, T.J. (deposition date: 2006-02-02, release date: 2006-06-13, Last modification date: 2023-08-30)

• Primary citation: Constantine, C.Z.,Starks, C.M.,Mill, C.P.,Ransome, A.E.,Karpowicz, S.J.,Francois, J.A.,Goodman, R.A.,Kappock, T.J.; Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti.; Biochemistry, 45:8193-8208, 2006; PubMed: 16819818; DOI: 10.1021/bi060465n

Experimental method

X-RAY DIFFRACTION (1.85 Å)