2FSO
mitogen activated protein kinase p38alpha (D176A) activating mutant
Summary for 2FSO
Entry DOI | 10.2210/pdb2fso/pdb |
Related | 2FSL 2FSM 2FST |
Descriptor | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside (3 entities in total) |
Functional Keywords | mitogen activated protein kinase, p38, active mutants, lipids, map kinase insertion, autophosphorylation, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 42491.51 |
Authors | Diskin, R.,Livnah, O. (deposition date: 2006-01-23, release date: 2006-12-05, Last modification date: 2024-05-29) |
Primary citation | Diskin, R.,Lebendiker, M.,Engelberg, D.,Livnah, O. Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation J.Mol.Biol., 365:66-76, 2007 Cited by PubMed: 17059827DOI: 10.1016/j.jmb.2006.08.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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