2FSD

A Common Fold for the Receptor Binding Domains of Lactococcal Phages? The Crystal Structure of the Head Domain of Phage bIL170

2FSD の概要

• エントリーDOI: 10.2210/pdb2fsd/pdb
• 分子名称: putative baseplate protein (2 entities in total)
• 機能のキーワード: phage, lactococcus lactis, receptor binding protein, head domain, viral protein
• 由来する生物種: unidentified phage
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30568.38

構造登録者

Ricagno, S.,Cambillau, C. (登録日: 2006-01-22, 公開日: 2006-09-05, 最終更新日: 2024-03-13)

主引用文献

Ricagno, S.,Campanacci, V.,Blangy, S.,Spinelli, S.,Tremblay, D.,Moineau, S.,Tegoni, M.,Cambillau, C.
Crystal Structure of the Receptor-Binding Protein Head Domain from Lactococcus lactis Phage bIL170
J.Virol., 80:9331-9335, 2006

PubMed Abstract: Lactococcus lactis, a gram-positive bacterium widely used by the dairy industry, is subject to lytic phage infections. In the first step of infection, phages recognize the host saccharidic receptor using their receptor binding protein (RBP). Here, we report the 2.30-A-resolution crystal structure of the RBP head domain from phage bIL170. The structure of the head monomer is remarkably close to those of other lactococcal phages, p2 and TP901-1, despite any sequence identity with them. The knowledge of the three-dimensional structures of three RBPs gives a better insight into the module exchanges which have occurred among phages.

PubMed: 16940545
DOI: 10.1128/JVI.01160-06

実験手法

X-RAY DIFFRACTION (2.3 Å)