2FLT

The X-ray structure of the cis-3-chloroacrylic acid dehalogenase cis-CaaD inactivated with (R)-Oxirane-2-carboxylate

2FLT の概要

• エントリーDOI: 10.2210/pdb2flt/pdb
• 分子名称: cis-3-chloroacrylic acid dehalogenase, LACTIC ACID (3 entities in total)
• 機能のキーワード: 3-chloroacrylic acid dehalogenase, 4ot family, hydratase, covalent inhibitor, 4-oxalocrotonate tautomerase, hydrolase
• 由来する生物種: coryneform bacterium
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16720.58

構造登録者

de Jong, R.M. (登録日: 2006-01-06, 公開日: 2006-11-21, 最終更新日: 2023-11-15)

• 主引用文献: de Jong, R.M.,Bazzacco, P.,Poelarends, G.J.,Johnson Jr., W.H.,Kim, Y.J.,Burks, E.A.,Serrano, H.,Thunnissen, A.M.,Whitman, C.P.,Dijkstra, B.W.; Crystal Structures of Native and Inactivated cis-3-Chloroacrylic Acid Dehalogenase: STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY AND INACTIVATION BY (R)-OXIRANE-2-CARBOXYLATE.; J.Biol.Chem., 282:2440-2449, 2007; PubMed: 17121835; DOI: 10.1074/jbc.M608134200

実験手法

X-RAY DIFFRACTION (2.1 Å)