2FJW

d(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment

Summary for 2FJW

Related1ZTW 2FJV 2FJX
Descriptor5'-D(*CP*TP*TP*GP*AP*AP*TP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*AP*AP*G)-3', Reverse transcriptase, ... (4 entities in total)
Functional Keywordsprotein-dna complex, drug-dna complex, water-mediated interaction, benzimidazole, minor groove, transferase-dna complex, transferase/dna
Biological sourceMoloney murine leukemia virus
Cellular locationGag-Pol polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p15: Virion . Capsid protein p30: Virion . Nucleocapsid protein p10: Virion  P03355
Total number of polymer chains3
Total molecular weight33786.53
Authors
Goodwin, K.D.,Georgiadis, M.M. (deposition date: 2006-01-03, release date: 2006-06-27, Last modification date: 2018-01-24)
Primary citation
Goodwin, K.D.,Lewis, M.A.,Tanious, F.A.,Tidwell, R.R.,Wilson, W.D.,Georgiadis, M.M.,Long, E.C.
A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128:7846-7854, 2006
PubMed: 16771498 (PDB entries with the same primary citation)
DOI: 10.1021/ja0600936
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.258195.1%2.7%13.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution