2FJV

RT29 Bound to D(CTTAATTCGAATTAAG) in complex with MMLV RT Catalytic Fragment

Summary for 2FJV

Related1ZTW 2FJW 2FJX
Descriptor5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', Reverse transcriptase, ... (5 entities in total)
Functional Keywordsmmlv rt, protein-dna complex, water-mediated interaction, drug-dna complex, rt29, benzamidazole, transferase-dna complex, transferase/dna
Biological sourceMoloney murine leukemia virus
Cellular locationGag-Pol polyprotein: Host cell membrane; Lipid-anchor (Potential). Matrix protein p15: Virion (Potential). Capsid protein p30: Virion (Potential). Nucleocapsid protein p10: Virion (Potential) P03355
Total number of polymer chains3
Total molecular weight34155.95
Authors
Goodwin, K.D.,Georgiadis, M.M. (deposition date: 2006-01-03, release date: 2006-06-27, Last modification date: 2011-07-13)
Primary citation
Goodwin, K.D.,Lewis, M.A.,Tanious, F.A.,Tidwell, R.R.,Wilson, W.D.,Georgiadis, M.M.,Long, E.C.
A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128:7846-7854, 2006
PubMed: 16771498 (PDB entries with the same primary citation)
DOI: 10.1021/ja0600936
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers182.4%3.1%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution