2FGT

Crystal Structure of YycH from Bacillus subtilis

2FGT の概要

• エントリーDOI: 10.2210/pdb2fgt/pdb
• 分子名称: Two-component system yycF/yycG regulatory protein yycH (2 entities in total)
• 機能のキーワード: signal transduction, yych, calcium binding, beta sheet, signaling protein
• 由来する生物種: Bacillus subtilis
• 細胞内の位置: Cell membrane ; Single-pass membrane protein : Q794W0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 47943.71

構造登録者

Szurmant, H.,Zhao, H.,Mohan, M.A.,James, H.A.,Varughese, K.I. (登録日: 2005-12-22, 公開日: 2006-04-25, 最終更新日: 2024-02-14)

主引用文献

Szurmant, H.,Zhao, H.,Mohan, M.A.,Hoch, J.A.,Varughese, K.I.
The crystal structure of YycH involved in the regulation of the essential YycFG two-component system in Bacillus subtilis reveals a novel tertiary structure.
Protein Sci., 15:929-934, 2006

PubMed Abstract: The Bacillus subtilis YycFG two-component signal transduction system is essential for cell viability, and the YycH protein is part of the regulatory circuit that controls its activity. The crystal structure of YycH was solved by two-wavelength selenium anomalous dispersion data, and was refined using 2.3 A data to an R-factor of 25.2%. The molecule is made up of three domains, and has a novel three-dimensional structure. The N-terminal domain features a calcium binding site and the central domain contains two conserved loop regions.

PubMed: 16600972
DOI: 10.1110/ps.052064406

実験手法

X-RAY DIFFRACTION (2.3 Å)