2FF5
Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal
Summary for 2FF5
| Entry DOI | 10.2210/pdb2ff5/pdb |
| Descriptor | Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol, ... (4 entities in total) |
| Functional Keywords | glycogenolysis; type 2 diabetes, transferase |
| Biological source | Oryctolagus cuniculus (rabbit) |
| Total number of polymer chains | 1 |
| Total formula weight | 97810.60 |
| Authors | Chrysina, E.D.,Kosmopoulou, M.N.,Leonidas, D.D.,Oikonomakos, N.G. (deposition date: 2005-12-19, release date: 2006-12-19, Last modification date: 2023-08-30) |
| Primary citation | He, L.,Zhang, Y.Z.,Tanoh, M.,Chen, G.-R.,Praly, J.-P.,Chrysina, E.D.,Tiraidis, C.,Kosmopoulou, M.,Leonidas, D.D.,Oikonomakos, N.G. In the Search of Glycogen Phosphorylase Inhibitors: Synthesis of C-D-Glycopyranosylbenzo(hydro)quinones Inhibition of and Binding to Glycogen Phosphorylase in the Crystal Eur.J.Org.Chem., 4:596-606, 2007 Cited by DOI: 10.1002/ejoc.200600548PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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