2FDQ

crystal structure of ACBP from Armadillo Harderian Gland

2FDQ の概要

• エントリーDOI: 10.2210/pdb2fdq/pdb
• 分子名称: Acyl-CoA-binding protein (2 entities in total)
• 機能のキーワード: acbp, diazepam binding inhibitor, transport protein
• 由来する生物種: Chaetophractus villosus (large hairy armadillo)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 29724.70

構造登録者

Costabel, M.D.,Guerin, D.M.A. (登録日: 2005-12-14, 公開日: 2006-10-24, 最終更新日: 2023-08-30)

主引用文献

Costabel, M.D.,Ermacora, M.R.,Santome, J.A.,Alzari, P.M.,Guerin, D.M.
Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family.
Acta Crystallogr.,Sect.F, 62:958-961, 2006

PubMed Abstract: The X-ray structure of the tetragonal form of apo acyl-CoA-binding protein (ACBP) from the Harderian gland of the South American armadillo Chaetophractus villosus has been solved. ACBP is a carrier for activated long-chain fatty acids and has been associated with many aspects of lipid metabolism. Its secondary structure is highly similar to that of the corresponding form of bovine ACBP and exhibits the unique flattened alpha-helical bundle (up-down-down-up) motif reported for animal, yeast and insect ACBPs. Conformational differences are located in loops and turns, although these structural differences do not suffice to account for features that could be related to the unusual biochemistry and lipid metabolism of the Harderian gland.

PubMed: 17012783
DOI: 10.1107/S1744309106038164

実験手法

X-RAY DIFFRACTION (3.5 Å)