2FAV
Crystal structure of SARS macro domain in complex with ADP-ribose at 1.8 A resolution
2FAV の概要
エントリーDOI | 10.2210/pdb2fav/pdb |
分子名称 | Replicase polyprotein 1ab (pp1ab) (ORF1AB), ADENOSINE-5-DIPHOSPHORIBOSE (3 entities in total) |
機能のキーワード | protein-adp-ribose complex, structural genomics, structural proteomics in europe, marseilles structural genomics program @ afmb, msgp, viral protein |
由来する生物種 | SARS coronavirus |
細胞内の位置 | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 59377.19 |
構造登録者 | Egloff, M.P.,Malet, H.,Marseilles Structural Genomics Program @ AFMB (MSGP) (登録日: 2005-12-08, 公開日: 2006-10-10, 最終更新日: 2011-07-13) |
主引用文献 | Egloff, M.P.,Malet, H.,Putics, A.,Heinonen, M.,Dutartre, H.,Frangeul, A.,Gruez, A.,Campanacci, V.,Cambillau, C.,Ziebuhr, J.,Ahola, T.,Canard, B. Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains. J.Virol., 80:8493-8502, 2006 Cited by PubMed: 16912299DOI: 10.1128/JVI.00713-06 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.8 Å) |
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