2F8M
Ribose 5-phosphate isomerase from Plasmodium falciparum
Summary for 2F8M
| Entry DOI | 10.2210/pdb2f8m/pdb |
| Descriptor | ribose 5-phosphate isomerase, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | structural genomics, psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, isomerase |
| Biological source | Plasmodium falciparum |
| Total number of polymer chains | 2 |
| Total formula weight | 54657.32 |
| Authors | Holmes, M.A.,Merritt, E.A.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (deposition date: 2005-12-02, release date: 2005-12-27, Last modification date: 2023-08-30) |
| Primary citation | Holmes, M.A.,Buckner, F.S.,Van Voorhis, W.C.,Verlinde, C.L.,Mehlin, C.,Boni, E.,DeTitta, G.,Luft, J.,Lauricella, A.,Anderson, L.,Kalyuzhniy, O.,Zucker, F.,Schoenfeld, L.W.,Earnest, T.N.,Hol, W.G.,Merritt, E.A. Structure of ribose 5-phosphate isomerase from Plasmodium falciparum. Acta Crystallogr.,Sect.F, 62:427-431, 2006 Cited by PubMed Abstract: The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms resolution. The enzyme, which catalyzes the isomerization reaction that interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of the pentose phosphate pathway. The P. falciparum enzyme belongs to the ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and is structurally similar to other members of the family. PubMed: 16682767DOI: 10.1107/S1744309106010876 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.087 Å) |
Structure validation
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