2F8M

Ribose 5-phosphate isomerase from Plasmodium falciparum

2F8M の概要

• エントリーDOI: 10.2210/pdb2f8m/pdb
• 分子名称: ribose 5-phosphate isomerase, PHOSPHATE ION (3 entities in total)
• 機能のキーワード: structural genomics, psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, isomerase
• 由来する生物種: Plasmodium falciparum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54657.32

構造登録者

Holmes, M.A.,Merritt, E.A.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (登録日: 2005-12-02, 公開日: 2005-12-27, 最終更新日: 2023-08-30)

主引用文献

Holmes, M.A.,Buckner, F.S.,Van Voorhis, W.C.,Verlinde, C.L.,Mehlin, C.,Boni, E.,DeTitta, G.,Luft, J.,Lauricella, A.,Anderson, L.,Kalyuzhniy, O.,Zucker, F.,Schoenfeld, L.W.,Earnest, T.N.,Hol, W.G.,Merritt, E.A.
Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62:427-431, 2006

PubMed Abstract: The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms resolution. The enzyme, which catalyzes the isomerization reaction that interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of the pentose phosphate pathway. The P. falciparum enzyme belongs to the ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and is structurally similar to other members of the family.

PubMed: 16682767
DOI: 10.1107/S1744309106010876

実験手法

X-RAY DIFFRACTION (2.087 Å)