2EZF

SOLUTION STRUCTURE OF A COMPLEX OF THE THIRD DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, MINIMIZED AVERAGE STRUCTURE

2EZF の概要

• エントリーDOI: 10.2210/pdb2ezf/pdb
• 分子名称: DNA (5'-D(*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3'), HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y (3 entities in total)
• 機能のキーワード: dna binding protein, minor groove dna binding, transcriptional co-activator, architectural factor, complex (dna-binding protein-dna), dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P17096
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 8510.28

構造登録者

Clore, G.M.,Huth, J.R.,Bewley, C.,Gronenborn, A.M. (登録日: 1997-06-04, 公開日: 1997-10-15, 最終更新日: 2022-03-09)

• 主引用文献: Huth, J.R.,Bewley, C.A.,Nissen, M.S.,Evans, J.N.,Reeves, R.,Gronenborn, A.M.,Clore, G.M.; The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif.; Nat.Struct.Biol., 4:657-665, 1997; PubMed: 9253416; DOI: 10.1038/nsb0897-657

実験手法

SOLUTION NMR